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J Frank Selected Research

Porphyrias (Porphyria)

3/2016[Erythropoietic protoporphyria : Clinical manifestations, diagnosis and new therapeutic possibilities].
3/2016[Neurocutaneous porphyrias].
3/2016[Porphyrias : Metabolic disorders of heme biosynthesis].
3/2016[Diagnosis of the porphyrias : From A (as in aminolevulinic acid) to Z (as in zinc protoporphyrin)].
1/2010The porphyrias: clinic, diagnostics, novel investigative tools and evolving molecular therapeutic strategies.
6/2006[Laboratory tests and therapeutic strategies for the porphyrias].
5/2006The porphyrias: clinical presentation, diagnosis and treatment.
1/2006Identification of mutations in the uroporphyrinogen III cosynthase gene in German patients with congenital erythropoietic porphyria.
1/2006European porphyria initiative (EPI): a platform to develop a common approach to the management of porphyrias and to promote research in the field.
1/2006Demystification of Chester porphyria: a nonsense mutation in the Porphobilinogen Deaminase gene.
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J Frank Research Topics

Disease

11Porphyrias (Porphyria)
03/2016 - 11/2001
5Neoplasms (Cancer)
06/2014 - 04/2000
5Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
02/2012 - 01/2001
4Alcoholism (Alcohol Abuse)
03/2015 - 06/2006
3Erythropoietic Protoporphyria
03/2016 - 06/2009
3Inflammation (Inflammations)
08/2014 - 08/2005
2Metabolic Diseases (Metabolic Disease)
03/2016 - 06/2006
2Edema (Dropsy)
07/2009 - 09/2000
2Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
07/2009 - 04/2001
2Acute Intermittent Porphyria (Porphyria, Acute)
07/2009 - 01/2006
2Body Weight (Weight, Body)
12/2008 - 04/2000
2Porphyria Cutanea Tarda
09/2007 - 01/2006
2Infections
01/2006 - 09/2003
1Poisoning
01/2022
1Major Depressive Disorder (Major Depressive Disorders)
01/2022
1Schizophrenia (Dementia Praecox)
01/2019
1Diabetes Mellitus
04/2018
1Sepsis (Septicemia)
04/2018
1Necrotizing Fasciitis
04/2018
1Wounds and Injuries (Trauma)
10/2017
1Lymphocytosis
07/2016
1Cryptogenic Organizing Pneumonia
07/2016
1Autoimmune Diseases (Autoimmune Disease)
07/2016
1Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)
07/2016
1Bronchiolitis
07/2016
1Interstitial Lung Diseases (Interstitial Lung Disease)
07/2016
1Idiopathic Pulmonary Fibrosis
07/2016
1Huntington Disease (Huntington's Disease)
01/2016
1Osteogenesis Imperfecta (Lobstein Disease)
04/2015
1Mania (Manias)
08/2014
1Cocaine-Related Disorders (Cocaine Addiction)
05/2014
1Alzheimer Disease (Alzheimer's Disease)
01/2014
1Tobacco Use Disorder (Nicotine Dependence)
10/2013
1Cardiovascular Diseases (Cardiovascular Disease)
05/2013
1Atherosclerosis
05/2013
1Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2013
1Breast Neoplasms (Breast Cancer)
03/2013
1Liver Neoplasms (Liver Cancer)
03/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
03/2013
1Thrombosis (Thrombus)
01/2013
1Renal Cell Carcinoma (Grawitz Tumor)
10/2012
1Nevus (Nevi)
10/2012
1Pigmented Nevus (Melanocytic Nevus)
10/2012
1Myasthenia Gravis
10/2012
1Leiomyoma (Uterine Fibroids)
01/2011
1Hereditary leiomyomatosis and renal cell cancer
01/2011
1Kidney Neoplasms (Kidney Cancer)
01/2011

Drug/Important Bio-Agent (IBA)

16Heme (Haem)IBA
03/2016 - 01/2001
11EnzymesIBA
03/2016 - 01/2001
5Protoporphyrinogen Oxidase (Protox)IBA
02/2012 - 01/2001
3Proteins (Proteins, Gene)FDA Link
07/2016 - 10/2012
3Ferrochelatase (Heme Synthetase)IBA
03/2016 - 06/2009
3Biological ProductsIBA
05/2014 - 08/2005
3Biomarkers (Surrogate Marker)IBA
05/2013 - 02/2003
3Anti-Bacterial Agents (Antibiotics)IBA
07/2004 - 08/2001
2Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2019 - 03/2015
2Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA
07/2009 - 01/2006
2Guanosine Triphosphate (GTP)IBA
12/2008 - 08/2001
2Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA
09/2007 - 01/2006
2Pharmaceutical PreparationsIBA
01/2006 - 09/2003
2IronIBA
08/2005 - 08/2002
1SulfurIBA
01/2022
1Antidepressive Agents (Antidepressants)IBA
01/2022
1NicotineFDA Link
07/2016
1AlbuminsIBA
07/2016
1zinc protoporphyrinIBA
03/2016
1Aminolevulinic Acid (Levulan)FDA Link
03/2016
1Protein Kinases (Protein Kinase)IBA
01/2016
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
04/2015
1Proteasome Endopeptidase Complex (Proteasome)IBA
08/2014
1UbiquitinIBA
08/2014
1Carrier Proteins (Binding Protein)IBA
05/2014
1SynucleinsIBA
05/2014
1MicellesIBA
01/2014
1CurcuminIBA
01/2014
1Cholinergic Agents (Cholinergics)IBA
10/2013
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
10/2013
1Apolipoproteins E (ApoE)IBA
05/2013
1ApolipoproteinsIBA
05/2013
1Vasodilator Agents (Vasodilators)IBA
05/2013
1QuercetinIBA
05/2013
1PolyphenolsIBA
05/2013
1Protein Isoforms (Isoforms)IBA
05/2013
1Long Noncoding RNAIBA
03/2013
1Polycomb Repressive Complex 2IBA
03/2013
1Untranslated RNA (Noncoding RNA)IBA
03/2013
1InterferonsIBA
03/2013
1Azathioprine (Imuran)FDA LinkGeneric
10/2012
1Mycophenolic Acid (Cellcept)FDA LinkGeneric
10/2012
1DNA (Deoxyribonucleic Acid)IBA
10/2012
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2012
1Atrial Natriuretic Factor (ANF)IBA
10/2011
1Acamprosate (Campral)FDA Link
10/2011
1Naltrexone (ReVia)FDA LinkGeneric
10/2011
1GATA4 Transcription FactorIBA
10/2011
1Fumarate Hydratase (Fumarase)IBA
01/2011

Therapy/Procedure

11Therapeutics
04/2018 - 03/2000
2Surgical Amputation (Amputations)
04/2018 - 10/2017
1Electrodes (Electrode)
01/2022
1Critical Care (Surgical Intensive Care)
04/2018